Article

Exploring the synergistic behaviour of paclitaxel and vorinostat upon co-loading in albumin nanoparticles for breast cancer management

2023-05-24

Abstract excerpt

<title>Abstract</title> <p>Breast cancer is challenging to treat accompanied with poor clinical outcomes. Paclitaxel (PTX) is a first-line chemotherapeutic agent, but possesses limitations due to side effects, high dose, non-specific tissue distribution, and drug resistance. An epigenetic modulator, Vorinostat (VOR) is known to enhance PTX efficacy and therefore to resolve the issues of conventional PTX formulati...

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Literature Corpus work: b00bb165-4781-500f-acd1-d8ed82593567
DOI: 10.21203/rs.3.rs-2928600/v1

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