Article

Comparative genomics analysis of three conserved plasmid families in the Western Hemisphere soft tick-borne relapsing fever borreliae provides insight into variation in genome structure and antigenic variation systems

2023-03-06

Abstract excerpt

Borrelia spirochetes, causative agents of Lyme disease and relapsing fever (RF), have a uniquely complex genome consisting of a linear chromosome and circular and linear plasmids. The plasmids harbor genes important for the vector-host life cycle of these tick-borne bacteria. The role of Lyme disease causing Borrelia plasmids is more refined compared to RF spirochetes because of limited plasmid-resolved genomes f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d5295fa1-e72f-5815-8bd5-582312432028
DOI: 10.1101/2023.03.06.531354

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Comparative genomics analysis of three conserved plasmid families in the Western Hemisphere soft tick-borne relapsing fever borreliae provides insight into variation in genome structure and antigenic variation systemsDOI 10.1101/2023.03.06.531354Read

Comparative genomics of the Western Hemisphere soft tick-borne relapsing fever borreliae highlights extensive plasmid diversitySemantic proximity Read

Large Linear Plasmids of Borrelia Species That Cause Relapsing FeverSemantic proximity Read

Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination.Semantic proximity Read

Whole genome sequencing of <i>Borrelia burgdorferi</i> isolates reveals linked clusters of plasmid-borne accessory genome elements associated with virulenceSemantic proximity Read

Complex exchanges among plasmids and clonal expansion of lineages shape the population structure and virulence of <i>Borrelia burgdorferi</i>Semantic proximity Read

Multipartite Genome of Lyme Disease Borrelia: Structure, Variation and ProphagesSemantic proximity Read

Natural selection and recombination at host-interacting lipoprotein loci drive genome diversification of Lyme disease and related bacteria.Semantic proximity Read

Characterisation and comparative genomics of three new Varanus-associated Borrelia spp. from Indonesia and AustraliaSemantic proximity Read

Multiple and Diverse vsp and vlp Sequences in Borrelia miyamotoi, a Hard Tick-Borne Zoonotic PathogenSemantic proximity Read

Characterization and genomic analysis of the Lyme disease spirochete bacteriophage ϕBB-1Semantic proximity Read

Whole genome sequencing of Borrelia miyamotoi isolate Izh-4: reference for a complex bacterial genomeSemantic proximity Read

Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids.Semantic proximity Read