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Article

Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids.

PloS one - 1 Jan 2012

Casjens Sherwood R, Mongodin Emmanuel F, Qiu Wei-Gang, Luft Benjamin J, Schutzer Steven E, Gilcrease Eddie B, Huang Wai Mun, Vujadinovic Marija, Aron John K, Vargas Levy C, Freeman Sam, Radune Diana, Weidman Janice F, Dimitrov George I, Khouri Hoda M, Sosa Julia E, Halpin Rebecca A, Dunn John J, Fraser Claire M

Abstract excerpt

Lyme disease is the most common tick-borne human illness in North America. In order to understand the molecular pathogenesis, natural diversity, population structure and epizootic spread of the North American Lyme agent, Borrelia burgdorferi sensu stricto, a much better understanding of the natural diversity of its genome will be required. Towards this end we present a comparative analysis of the nucleotide...

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Identifiers

PMID: 22432010
DOI: 10.1371/journal.pone.0033280
PMCID: PMC3303823

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