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Large Linear Plasmids of Borrelia Species That Cause Relapsing Fever

8 Jun 2013

Abstract excerpt

Borrelia species of relapsing fever (RF) and Lyme disease (LD) lineages have linear chromosomes and both linear and circular plasmids. Unique to RF species, and little characterized to date, are large linear plasmids of ∼160 kb, or ∼10% of the genome. By a combination of Sanger and next-generation methods, we determined the sequences of large linear plasmids of two New World species: Borrelia hermsii, to...

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PMID: 23749977
DOI: 10.1128/jb.00347-13

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