Article

Complex exchanges among plasmids and clonal expansion of lineages shape the population structure and virulence of <i>Borrelia burgdorferi</i>

2025-01-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In the United States, Borrelia burgdorferi ( Bb ) is the principal etiologic agent of Lyme disease. The complex structure of Bb genomes has posed challenges for genomic studies because homology among the bacterium’s many plasmids, which account for ∼40% of the genome by length, has made them difficult to sequence and assemble. <h4>Results</h4> We used long-read sequenci...

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Literature Corpus work: 635e7f4b-8fb8-5576-97c2-84a003162fd7
DOI: 10.1101/2025.01.29.635312

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