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Natural selection and recombination at host-interacting lipoprotein loci drive genome diversification of Lyme disease and related bacteria.

mBio - 11 Sept 2024

Akther Saymon, Mongodin Emmanuel F, Morgan Richard D, Di Lia, Yang Xiaohua, Golovchenko Maryna, Rudenko Natalie, Margos Gabriele, Hepner Sabrina, Fingerle Volker, Kawabata Hiroki, Norte Ana Cláudia, de Carvalho Isabel Lopes, Núncio Maria Sofia, Marques Adriana, Schutzer Steven E, Fraser Claire M, Luft Benjamin J, Casjens Sherwood R, Qiu Weigang

Abstract excerpt

Lyme disease, caused by spirochetes in the Borrelia burgdorferi sensu lato clade within the Borrelia genus, is transmitted by Ixodes ticks and is currently the most prevalent and rapidly expanding tick-borne disease in Europe and North America. We report complete genome sequences of 47 isolates that encompass all established species in this clade while highlighting the diversity of the widespread human pathogenic...

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Identifiers

PMID: 39145656
DOI: 10.1128/mbio.01749-24
PMCID: PMC11389397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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