Article

Regulation of Hippo/YAP signaling and esophageal squamous carcinoma progression by an E3 ubiquitin ligase PARK2

2020-03-18

Abstract excerpt

<title>Abstract</title> <p>Background Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies in the world, while the overall five-year survival is less than 20%. Recent genomic sequencing analysis indicated the over-activation of Hippo/YAP signaling might play important roles for the carcinogenic process and progression for ESCC patients. However, little is known about the molecular mech...

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Literature Corpus work: d520dc61-ce73-5983-ab77-d90f29464cd0
DOI: 10.21203/rs.3.rs-17746/v1

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