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STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinoma

2023-06-16

Abstract excerpt

<h4>Purpose: </h4> Esophageal squamous cell carcinoma (ESCC) is an aggressive disease with a poor prognosis, caused by the inactivation of critical cell growth regulators that lead to uncontrolled proliferation and increased malignancy. Although Serine/Threonine Kinase 3 (STK3), also known as Mammalian STE20-like protein kinase 2 (MST2), is a highly conserved kinase of the Hippo pathway, plays a critical role in i...

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Literature Corpus work
e602c866-b651-5da8-951f-300974f439ca
DOI
10.21203/rs.3.rs-3058891/v1
Open publication

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STK3 kinase activation inhibits tumor proliferation through FOXO1-TP53INP1/P21 pathway in esophageal squamous cell carcinomaDOI 10.21203/rs.3.rs-3058891/v1
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