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PIWIL2 interacting with IKK to regulate autophagy and apoptosis in esophageal squamous cell carcinoma

19 Jan 2021

Abstract excerpt

Esophageal squamous cell carcinoma (ESCC) is one of the most common malignancies and cause of death from cancer in China. Previous studies showed that autophagy and apoptosis inhibition are critical for the survival of ESCC cells. However, the underlying mechanisms remain to be clarified. Recently, we found that PIWIL2, a novel cancer testis protein, is highly expressed in ESCC and associated with high T-stage...

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PMID: 33469229
DOI: 10.1038/s41418-020-00725-4

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