Article

Simulating the Influence of Conjugative Plasmids Kinetic Values on the Multilevel Dynamics of Antimicrobial Resistance in a Membrane Computing Model

2020-03-29

Abstract excerpt

Plasmids harboring antibiotic resistance genes differ in their kinetic values as plasmid conjugation rate, segregation rate by incompatibility with related plasmids, rate of stochastic loss during replication, cost reducing the host-cell fitness, and frequency of compensatory mutations to reduce plasmid cost, depending on the cell mutation frequency. How variation in these values influence the success of a plasmid...

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Identifiers and source

Literature Corpus work: 94be8435-7803-5b28-9034-27d860ceb18b
DOI: 10.1101/2020.03.27.012955

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