Article

Gene-level alignment of single cell trajectories

2023-03-10

Abstract excerpt

Single-cell data analysis can infer dynamic changes in cell populations, for example across time, space or in response to perturbation. To compare these dynamics between two conditions, trajectory alignment via dynamic programming (DP) optimization is frequently used, but is limited by assumptions such as a definite existence of a match. Here we describe Genes2Genes , a Bayesian information-theoretic DP framework...

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Literature Corpus work: d512664f-77e9-5390-aa47-8db90cf937c4
DOI: 10.1101/2023.03.08.531713

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