Article

The Co-Evolution of Jawed Vertebrates and Interferon Regulatory Factor 5 Generates Unique Inflammation and Innate Immunity

2024-07-16

Abstract excerpt

The emergence of jaws in early vertebrates introduced a novel feeding apparatus and potent oral defenses but also increased the risk of physical injury and pathogen exposure. Innate immunity and inflammation constitute the body’s first line of defense against invading microbes and tissue damage, aiming to eliminate threats and restore internal homeostasis. Interferon regulatory factor 5 (IRF5) plays a critical rol...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d506cc74-b393-50db-bf58-e16e617b56b0
DOI: 10.22541/au.172115472.23265778/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Co-Evolution of Jawed Vertebrates and Interferon Regulatory Factor 5 Generates Unique Inflammation and Innate ImmunityDOI 10.22541/au.172115472.23265778/v1Read

The Co-Evolution of Jawed Vertebrates and Interferon Regulatory Factor 5 Generates Unique Inflammation and Innate ImmunitySemantic proximity Read

Global characterization of interferon regulatory factor (IRF) genes in vertebrates: glimpse of the diversification in evolution.Semantic proximity Read

Evolution of vertebrate interferon inducible transmembrane proteinsSemantic proximity Read

Interferon Regulatory Factors (IRF1, IRF4, IRF5, IRF7 and IRF9) in Sichuan taimen (Hucho bleekeri): Identification and Functional CharacterizationSemantic proximity Read

Regulating IRFs in IFN Driven DiseaseSemantic proximity Read

Interferon-stimulated genes in zebrafish and human define an ancient arsenal of antiviral immunitySemantic proximity Read

Functional Characterization of Murine Interferon Regulatory Factor 5 (IRF-5) and Its Role in the Innate Antiviral ResponseSemantic proximity Read

Identification of Fish Interferon Stimulated Genes and Their Antiviral MechanismsSemantic proximity Read

Characterization of common carp (Cyprinus carpio L.) interferon regulatory factor 5 (IRF5) and its expression in response to viral and bacterial challengesSemantic proximity Read

Sequence and Expression Analysis of Interferon Regulatory Factor 10 (IRF10) in Three Diverse Teleost Fish Reveals Its Role in Antiviral DefenseSemantic proximity Read

Characterization of fish IRF3 as an IFN-inducible protein reveals evolving regulation of IFN response in vertebrates.Semantic proximity Read

Expansion of amphibian intronless interferons revises the paradigm for interferon evolution and functional diversity.Semantic proximity Read