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Exosome Uptake from Lung Adenocarcinoma and Squamous Cell Carcinoma Alters T Cell Cytokine Expression and Modulates Protein Profiles in Exosome Biogenesis

2025-01-30

Abstract excerpt

Despite advances in immunotherapy, non-small cell lung carcinoma (NSCLC) clinical success is limited, possibly due to substantial immunological alterations in advanced cancer pa-tients. This study examines the immunomodulatory effects of exosomes derived from lung adeno-carcinoma (ADC) and squamous cell carcinoma (SCC) on T cells. <h4>Methods:</h4> Exosomes were isolated from A549 (lung adenocarcinoma), SKMES1 (lu...

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Literature Corpus work
000dfa31-d34b-528d-8292-f64c73aadac5
DOI
10.20944/preprints202501.2259.v1
Open publication

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