Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor-derived exosomes induce CD8+ T cell suppressors

2 Aug 2017

Abstract excerpt

Background The suppressive nature of immune cells in the tumor microenvironment plays a major role in regulating anti-tumor immune responses. Our previous work demonstrated that a soluble factor from tumor cells is able to induce a suppressor phenotype (SP) in human CD8+ T cells typified by loss of CD27/CD28 expression and acquisition of a potent suppressor function. The present study hypothesized that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Extracellular vesicles in disease
Share to Immune Cell Function and Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28806909
DOI: 10.1186/s40425-017-0269-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor-derived exosomes induce CD8+ T cell suppressorsPMID 28806909Read ↗

Roles of Cancer Exosomes in Immunosuppression and Immune EvasionSemantic proximity Read ↗

Tumor-derived exosomes and their application in cancer treatmentSemantic proximity Read ↗

An Immunosuppressive Effect of Melanoma-derived Exosomes on NY-ESO-1 Antigen-specific Human CD8+ T Cells is Dependent on IL-10 and Independent of BRAFV600E Mutation in Melanoma Cell Lines.Semantic proximity Read ↗

Evaluating tumor cell- and T cell-derived extracellular vesicles as potential biomarkers of cancer and immune cell competenceSemantic proximity Read ↗

Beyond Exosomes: Ultrapurified Phospholipoproteic Complex (PLPC) as a Scalable Immunomodulatory Platform to Reprogram Immune Suppression in Metastatic CancerSemantic proximity Read ↗

Tumor Exosomes: Cellular Postmen of Cancer Diagnosis and Personalized TherapySemantic proximity Read ↗

Exosomes in Cancer DiagnosticsSemantic proximity Read ↗

PD-L2 of tumor-derived exosomes mediates the immune escape of cancer cells via the impaired T cell functionSemantic proximity Read ↗

Extra-cellular vesicles carry proteome of cancer hallmarksSemantic proximity Read ↗

Single-cell transcriptome analysis of the immunosuppressive effect of differential expression of tumor PD-L1 on responding TCR-T cellsSemantic proximity Read ↗

Exosomes and Extracellular Vesicles in Myeloid Neoplasia: The Multiple and Complex Roles Played by These “Magic Bullets”Semantic proximity Read ↗

The regulatory role of long non- coding RNAs as a novel controller of immune response against cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.