Article

The role of Double Strand Break Repair, Translesion Synthesis and Interstrand Crosslinks in Colorectal Cancer progression – clinicopathological data and survival.

2019-06-24

Abstract excerpt

<title>Abstract</title> <p>Abstract Aim: To evaluate the prognostic value of molecular modulation of double strand break (DSBR) - XRCC2 and XRCC5 - core components; DNA damage tolerance/translesion synthesis (DDT/TLS) - POLH, POLK and POLQ – and, finally, of interstrand crosslink repair (ICLR) -DCLRE1A – pathways in sporadic colorectal cancer (CRC) progression. <h4>Method:</h4> Tumour specimens and matched health...

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Literature Corpus work: d4d63e41-9e18-53f2-a840-135defc78790
DOI: 10.21203/rs.2.10554/v1

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