Article
The role of XRCC4 in carcinogenesis and anticancer drug discovery.
Recent patents on anti-cancer drug discovery - 1 Nov 2008
Wu Cheng-Nan, Liang Shiu-Yun, Tsai Chia-Wen, Bau Da-Tian
Abstract excerpt
In the past decades, the incidence of cancer keeps its rapid increasing step all over the world and cancer is always an important threat to public health. It is believed that cancer is resulted from a series of genetic alterations leading to progressive disorder of the normal mechanisms controlling cell proliferation, differentiation, death, and/or genomic stability. The response of the cell to genetic injury and...
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