Article

Young BMSC-derived extracellular vesicles containing lncRNA sponging miR-1843a-5p to regulate Mob3a/YAP axis promote osteogenesis of senescent BMSCs

2023-09-13

Abstract excerpt

Bone repair in elderly patients poses a huge challenge due to the age-related progressive degenerative decline in regenerative abilities attributed to the senescence of bone marrow stem cells (BMSCs). Stem cell extracellular vesicles-mediated therapy are increasingly acknowledged as a promising strategy for delaying senescence and promoting osteogenesis. Osteoinductive exosome (OI-exo) derived from young BMSCs was...

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Literature Corpus work: d4d57302-9ffd-57ea-acbf-d265c079048a
DOI: 10.21203/rs.3.rs-3339133/v1

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