Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Site-Specific Integration of <i>TRAIL</i> in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer Therapy

1 Jan 2022

Abstract excerpt

Mesenchymal stem cells (MSCs) are a promising cellular vehicle for transferring anti-cancer factors to malignant tumors. Currently, a variety of anti-cancer agents, including the tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), have been loaded into MSCs derived from a range of sources through different engineering methods. These engineered MSCs exhibit enormous therapeutic potential for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mesenchymal stem cell research
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35267023
DOI: 10.1093/stcltm/szab031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Site-Specific Integration of <i>TRAIL</i> in iPSC-Derived Mesenchymal Stem Cells for Targeted Cancer TherapyPMID 35267023Read ↗

Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapySemantic proximity Read ↗

Human menstrual blood-derived mesenchymal stem cells as a cellular vehicle for malignant glioma gene therapySemantic proximity Read ↗

Human Bone Marrow-Derived Mesenchymal Stromal Cells Expressing S-TRAIL as a Cellular Delivery Vehicle for Human Glioma TherapySemantic proximity Read ↗

Human Adipose-Derived Stem Cells Genetically Programmed to Induce Necroptosis for Cancer ImmunotherapySemantic proximity Read ↗

CircRNA-Mediated Reprogramming of Adipose-Derived Stem Cells to iPSCs for Efficient Derivation of Functional Mesenchymal Stem CellsSemantic proximity Read ↗

pIL6-TRAIL-engineered umbilical cord mesenchymal/stromal stem cells are highly cytotoxic for myeloma cells both in vitro and in vivoSemantic proximity Read ↗

Combination of immortalization and inducible death strategies to generate a human mesenchymal stromal cell line with controlled survivalSemantic proximity Read ↗

Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung CancerSemantic proximity Read ↗

Generation of a novel TRAIL mutant by proline to arginine substitution based on codon bias and its antitumor effects.Semantic proximity Read ↗

Genetic Engineering of Umbilical MSCs Co-Expressing PD-1 and HSV-1-TK for Immune Activation and Tumor EradicationSemantic proximity Read ↗

Understanding and exploiting <i>hTERT</i> promoter regulation for diagnosis and treatment of human cancersSemantic proximity Read ↗

Auto-loaded TRAIL-exosomes derived from induced neural stem cells for brain cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.