Article

Transcription factor FOXM1 specifies the loading of chromatin DNA to extracellular vesicles

2022-01-28

Abstract excerpt

Extracellular vesicle DNAs (evDNAs) possess the important diagnostic value for multiple diseases and play roles for horizontally transferring genetic materials among cells. In this study, we have found that transcription factor FOXM1 can mediate the loading of certain chromatin genes or DNA fragments (named FOXM1-chDNAs) to extracellular vesicles (EVs). FOXM1 interacts with LC3 in nucleus and FOXM1-chDNAs (such as...

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Literature Corpus work: d4ac5c1b-6632-5436-9dcf-b325c8216a91
DOI: 10.1101/2022.01.27.477315

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