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Article

BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy

19 May 2015

Abstract excerpt

Knowledge of the mechanisms by which a cell detects exogenous DNA is important for controlling pathogen infection, because most pathogens entail the presence of exogenous DNA in the cytosol, as well as for understanding the cell's response to artificially transfected DNA. The cellular response to pathogen invasion has been well studied. However, spatiotemporal information of the cellular response immediately...

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PMID: 25991860
DOI: 10.1073/pnas.1501235112

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