Article
Horizontal transfer of nuclear DNA in transmissible cancer
2024-07-26
Abstract excerpt
<h4>Summary</h4> Although somatic cell genomes are usually entirely clonally inherited, nuclear DNA exchange between cells of an organism can occur sporadically by cell fusion, phagocytosis or other mechanisms 1–3 . This phenomenon has long been noted in the context of cancer, where it could be envisaged that DNA horizontal transfer plays a functional role in disease evolution 4–13 . However, an understanding o...
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Identifiers and source
- Literature Corpus work
- d499698a-8c6f-5173-b2f5-894257c10640
- DOI
- 10.1101/2024.07.26.604742