Article
Origins and evolution of a transmissible cancer.
Evolution; international journal of organic evolution - 1 Sept 2009
Rebbeck Clare A, Thomas Rachael, Breen Matthew, Leroi Armand M, Burt Austin
Abstract excerpt
Canine transmissible venereal tumor (CTVT) is an infectious disease of dogs. Remarkably, the infectious agent is the cancerous cell itself. To investigate its origin and spread, we collected 37 tumor samples from four continents and determined their evolutionary relationships using microsatellite length differences and microarray-based comparative genomic hybridization (aCGH). The different tumors show very...
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