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Article

Clonal origin and evolution of a transmissible cancer.

Cell - 11 Aug 2006

Murgia Claudio, Pritchard Jonathan K, Kim Su Yeon, Fassati Ariberto, Weiss Robin A

Abstract excerpt

The transmissible agent causing canine transmissible venereal tumor (CTVT) is thought to be the tumor cell itself. To test this hypothesis, we analyzed genetic markers including major histocompatibility (MHC) genes, microsatellites, and mitochondrial DNA (mtDNA) in naturally occurring tumors and matched blood samples. In each case, the tumor is genetically distinct from its host. Moreover, tumors collected from...

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Identifiers

PMID: 16901782
DOI: 10.1016/j.cell.2006.05.051
PMCID: PMC2593932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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