Article

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

2011-01-01

Abstract excerpt

Concentrations of liver enzymes in plasma are widely used as indicators of liver disease. We carried out a genome-wide association study in 61,089 individuals, identifying 42 loci associated with concentrations of liver enzymes in plasma, of which 32 are new associations (P = 10 -8 to P = 10 -190). We used functional genomic approaches including metabonomic profiling and gene expression analyses to identify probab...

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Literature Corpus work: d48986f6-8468-5cf5-bb10-d35432ac531a
DOI: 10.5451/unibas-ep81762

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