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Liver enzymes, metabolomics and genome-wide association studies: From systems biology to the personalized medicine

1 Jan 2015

Abstract excerpt

For several decades, serum levels of alanine (ALT) and aspartate (AST) aminotransferases have been regarded as markers of liver injury, including a wide range of etiologies from viral hepatitis to fatty liver. The increasing worldwide prevalence of metabolic syndrome and cardiovascular disease revealed that transaminases are strong predictors of type 2 diabetes, coronary heart disease, atherothrombotic risk...

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PMID: 25624707
DOI: 10.3748/wjg.v21.i3.711

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