Article

Extracellular Vesicles from iPSC-Derived Glial Progenitor Cells Prevent Glutamate-Induced Excitotoxicity by Stabilising Calcium Oscillations and Mitochondrial Depolarization

2025-11-04

Abstract excerpt

Neurodegenerative diseases pose a significant challenge to modern medicine. Despite significant advances in neurology, current therapeutic approaches often prove insufficient to treat such disorders. This study investigates the neuroprotective effect of extracellular vesicles derived from glial derivates of human induced pluripotent stem cells. The extra-cellular vesicle’s cargo was characterised by proteomic anal...

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Literature Corpus work: d3a0b43d-4634-598e-8db7-d2b549631c76
DOI: 10.20944/preprints202511.0105.v1

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