Article

Leigh Syndrome-inducing Mutations Affect LRPPRC / SLIRP Complex Formation

2020-04-18

Abstract excerpt

<h4>ABSTRACT</h4> Mitochondria are essential organelles carrying their own genetic information which require specific gene expression processes. The leucine rich pentatricopeptide protein (LRPPRC) and its partner the SRA stem-loop interacting RNA binding protein (SLIRP) form a stable complex implicated in mRNA stability and polyadenylation. LRPPRC/SLIRP complex formation is still poorly characterized. We demonstr...

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Literature Corpus work: d327ffaa-377b-538c-8ff3-cfdffe7ed781
DOI: 10.1101/2020.04.16.044412

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