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Article

SLIRP stabilizes LRPPRC via an RRM-PPR protein interface.

Nucleic acids research - 19 Aug 2016

Spåhr Henrik, Rozanska Agata, Li Xinping, Atanassov Ilian, Lightowlers Robert N, Chrzanowska-Lightowlers Zofia M A, Rackham Oliver, Larsson Nils-Göran

Abstract excerpt

LRPPRC is a protein that has attracted interest both for its role in post-transcriptional regulation of mitochondrial gene expression and more recently because numerous mutated variants have been characterized as causing severe infantile mitochondrial neurodegeneration. LRPPRC belongs to the pentatricopeptide repeat (PPR) protein family, originally defined by their RNA binding capacity, and forms a complex with...

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Source

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Identifiers

PMID: 27353330
DOI: 10.1093/nar/gkw575
PMCID: PMC5001613

Genes

SLIRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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SLIRP stabilizes LRPPRC via an RRM-PPR protein interface.PMID 27353330Read ↗

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A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression.Semantic proximity Read ↗

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