tRForest: a novel random forest-based algorithm for tRNA-derived fragment target prediction

Abstract excerpt

tRNA fragments (tRFs) are small RNAs comparable to the size and function of miRNAs. tRFs are generally Dicer independent, are found associated with Ago, and can repress expression of genes post-transcriptionally. Given that this expands the repertoire of small RNAs capable of post-transcriptional gene expression, it is important to predict tRF targets with confidence. Some attempts have been made to predict tRF ta...

Topics

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• Anticodon
• Cluster Analysis
• MCF-7 Cells
• Nucleic Acid Conformation
• RNA
• RNA, Mitochondrial
• RNA, Transfer
• Transcriptome

Identifiers and source

Literature Corpus work

d323f763-f3be-5c2d-9002-75cb2068842f

DOI

10.1101/2021.12.13.472430