Back to search

Article

PDGF-A Strengthens the Neurovascular Unit and Inhibits Retinal Vascular Regression Under Hyperoxic Conditions

2024-11-11

Abstract excerpt

Retinopathy of prematurity (ROP) is primarily caused by exposure of preterm infants with underdeveloped blood vessels to high oxygen concentrations. This damages the astrocytes that promote normal vascular development, leading to avascularity, pathological neovascularization, and retinal detachment, and even blindness as the disease progresses. This study aimed to investigate the differences in the characteristics...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d30675d4-2258-5d68-b484-0a1ae2e7f8a8
DOI
10.20944/preprints202411.0671.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
PDGF-A Strengthens the Neurovascular Unit and Inhibits Retinal Vascular Regression Under Hyperoxic ConditionsDOI 10.20944/preprints202411.0671.v1
Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy.Semantic proximity
PDGF mediates a neuron-astrocyte interaction in the developing retina.Semantic proximity
The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse ModelSemantic proximity
Animal Models of Retinopathy of Prematurity: Advances and Metabolic RegulatorsSemantic proximity
Roles of HIFs and VEGF in angiogenesis in the retina and brainSemantic proximity
Plastic roles of pericytes in the blood–retinal barrierSemantic proximity
Vascular Endothelial Growth Factor Signaling in Models of Oxygen-Induced Retinopathy: Insights Into Mechanisms of Pathology in Retinopathy of PrematuritySemantic proximity
The pathophysiology of retinopathy of prematurity: an update of previous and recent knowledgeSemantic proximity
Hypoxia inducible factor-2α regulates the development of retinal astrocytic network by maintaining adequate supply of astrocyte progenitors.Semantic proximity
Astrocytes follow ganglion cell axons to establish an angiogenic template during retinal development.Semantic proximity
Müller cells and retinal angiogenesis: critical regulators in health and diseaseSemantic proximity
Pericytes and the Pathogenesis of Diabetic RetinopathySemantic proximity
Select a neighboring publication to make it the new centre.