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Article

PDGF mediates a neuron-astrocyte interaction in the developing retina.

Neuron - 1 Dec 1996

Fruttiger M, Calver A R, Krüger W H, Mudhar H S, Michalovich D, Takakura N, Nishikawa S, Richardson W D

Abstract excerpt

Astrocytes invade the developing retina from the optic nerve head, over the axons of retinal ganglion cells (RGCs). RGCs express the platelet-derived growth factor A-chain (PDGF-A) and retinal astrocytes the PDGF alpha-receptor (PDGFR alpha), suggesting that PDGF mediates a paracrine interaction...

Topics

Animals
Animals, Newborn
Astrocytes
COS Cells
Cell Communication
Cell Division
Mice
Mice, Transgenic
Nerve Net
Neurons
Phenotype
Platelet-Derived Growth Factor
Rats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptor, Platelet-Derived Growth Factor alpha

Receptors, Platelet-Derived Growth Factor

Retina

Retinal Vessels

Source

Identifiers

PMID: 8982160
DOI: 10.1016/s0896-6273(00)80244-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8982160-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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