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Article

Platelet-derived growth factor-A-induced retinal gliosis protects against ischemic retinopathy.

The American journal of pathology - 1 Feb 2000

Yamada H, Yamada E, Ando A, Seo M S, Esumi N, Okamoto N, Vinores M, LaRochelle W, Zack D J, Campochiaro P A

Abstract excerpt

Retinal astrocytes are located in the nerve fiber layer and along retinal blood vessels and have been hypothesized to participate in the induction and maintenance of the blood-retinal barrier. Platelet-derived growth factor-A (PDGF-A) is normally produced by retinal ganglion cells and is involved in astrocyte recruitment and proliferation. We used gain-of-function transgenic mice that express PDGF-A in...

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Identifiers

PMID: 10666377
DOI: 10.1016/S0002-9440(10)64752-9
PMCID: PMC1850030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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