Article

Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi

2023-06-12

Abstract excerpt

<h4>Background: </h4> Tuberculosis (TB) remains a major challenge in many domains including diagnosis, pathogenesis, prevention, treatment, drug resistance and long-term protection of the public health by vaccination. A controlled human infection model (CHIM) could potentially facilitate breakthroughs in each of these domains but has so far been considered impossible owing to technical and safety concerns. <h4>Me...

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Literature Corpus work: d3035db6-1639-5a87-b9cc-52cdea1d3a32
DOI: 10.12688/wellcomeopenres.18767.2

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