Article
Intracellular auto-circularizing RNA using human tRNA splicing elements
2025-07-31
Abstract excerpt
Circular RNAs (circRNAs), a type of covalently closed RNA, have emerged as crucial regulatory factors in gene expression and development across various organisms. Understanding their formation and functional mechanisms holds potential for therapeutic applications, including novel RNA vaccines against diseases such as COVID-19. However, practical challenges still exist in the preparation of circRNAs. In this study,...
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Identifiers and source
- Literature Corpus work
- 80d53f6d-7504-5044-9695-7cdd8cf3b22f
- DOI
- 10.1101/2025.07.28.667085