Article

Patterns of Chromosomal Instability and Clonal Heterogeneity in Luminal B Breast Cancer

2024-02-12

Abstract excerpt

Chromosomal instability (CIN), defined by variations in the number or structure of chromosomes from cell to cell, is recognized as a distinctive characteristic of cancer, associated with the ability of tumors to adapt to challenging environments. CIN has been recognized as a source of genetic variation that leads to clonal heterogeneity (CH). Recent findings suggest a potential association between CIN and CH with...

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Literature Corpus work: d2aba6e6-fdbc-5db9-af5a-a24eaf104b9e
DOI: 10.20944/preprints202402.0621.v1

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