Article

Altering lipid droplet homeostasis affects <i>Coxiella burnetii</i> intracellular growth

2017-03-01

Abstract excerpt

<h4>ABSTRACT</h4> Coxiella burnetii is an obligate intracellular bacterial pathogen and a causative agent of culture-negative endocarditis. While C. burnetii initially infects alveolar macrophages, it has also been found in lipid droplet (LD)-containing foamy macrophages in the cardiac valves of endocarditis patients. In addition, transcriptional studies of C. burnetii -infected macrophages reported differentia...

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Literature Corpus work: d2a30ab0-6962-5865-9072-233e1c9d489c
DOI: 10.1101/112300

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