Article

Acetate, a short-chain fatty acid, inhibits Coxiella burnetii replication via direct bacteriostatic effect and through vacuolar modulation and host cell perturbations

2026-07-28

Abstract excerpt

<title>Abstract</title> <italic> <bold>Background</bold> </italic> <italic>Coxiella burnetii</italic> , the etiologic agent of Q fever, is an obligate intracellular pathogen that replicates within a specialized acidic compartment termed the <italic>Coxiella</italic> -containing vacuole (CCV). Current treatment options for chronic Q fever require prolonged antibiotic therapy and are limited by toxicity...

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Literature Corpus work: 4acba555-5572-59aa-9761-7b89541437bb
DOI: 10.21203/rs.3.rs-10474872/v1

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