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Three-dimensional quantitative characterization of <i>Coxiella burnetii</i> infection using focused ion beam-scanning electron microscopy

2025-01-04

Abstract excerpt

<h4>ABSTRACT</h4> Coxiella burnetii is a highly virulent intracellular pathogen that causes acute and chronic Q fever in humans. The bacterium utilizes a Dot/Icm type IV secretion system (T4SS) to translocate over 100 effectors into host cells to facilitate biogenesis of Coxiella -containing vacuoles (CCVs), which are specialized lysosome-derived organelles that support bacterial replication. During replication...

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Literature Corpus work
d56e5889-ce95-53da-a5cc-12fe9c948000
DOI
10.1101/2025.01.03.631259
Open publication

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Three-dimensional quantitative characterization of <i>Coxiella burnetii</i> infection using focused ion beam-scanning electron microscopyDOI 10.1101/2025.01.03.631259
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