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<i>Streptococcus mitis</i> bacteriocins drive contact-dependent lysis of <i>S. pneumoniae</i> facilitating transformation in multispecies environments

2025-08-25

Abstract excerpt

Natural competence allows bacterial species like Streptococcus pneumoniae and S. mitis to acquire environmental DNA, driving horizontal gene transfer (HGT) and adaptation. In S. pneumoniae , a human pathogen, competence-induced predation is well characterized and involves the release of bacteriocins and a murein hydrolase to lyse noncompetent siblings and liberate DNA. In contrast, in the human commensal S. mi...

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Literature Corpus work
ad8d9c18-10f8-5584-acb0-cb58c1ce70f1
DOI
10.1101/2025.08.25.672098
Open publication

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