Article

Effects of steroid-resistant nephrotic syndrome serum on AA pathway in podocytes cultured in 3D in vitro glomerular model

2024-08-09

Abstract excerpt

<title>Abstract</title> <p>Background and hypothesis. Steroid-resistant nephrotic syndrome (SRNS) is the most severe form of nephrotic syndrome, with genetic or unidentified immunological origins and rapidly progressing to the need for kidney replacement therapy. Lipotoxicity can affect podocytes inducing kidney damage. In this study, we evaluate the effects of SRNS serum on podocyte functionality and lipid meta...

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Literature Corpus work: d294ecef-8433-5982-a45a-8ace8fc78201
DOI: 10.21203/rs.3.rs-4684821/v1

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