Article

Nephrotic Syndrome-Associated Hypercoagulopathy is Alleviated by Nuclear Receptor Agonist Therapy with both Pioglitazone and Glucocorticoids

2020-01-07

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Thrombosis is a potentially life-threatening nephrotic syndrome (NS) complication. We have previously demonstrated that hypercoagulopathy is proportional to NS severity in rat models and that pioglitazone (Pio) reduces proteinuria both independently and in combination with methylprednisolone (MP), a glucocorticoid (GC). However, the effect of these treatments on NS-associate...

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Literature Corpus work: 9510089b-4f9f-528b-a636-7891623b05d1
DOI: 10.1101/2020.01.07.897751

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