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Article

Glomerular Transcriptome Profiles in Focal Glomerulosclerosis: New Genes and Pathways for Steroid Resistance.

American journal of nephrology - 1 Jan 2020

Tong Jun, Jin Yuanmeng, Weng Qinjie, Yu Shuwen, Jafar Hussain Hafiz Muhammad, Ren Hong, Xu Jing, Zhang Wen, Li Xiao, Wang Weiming, Xie Jingyuan, Chen Nan

Abstract excerpt

BACKGROUND: Patients with focal segmental glomerulosclerosis (FSGS) characterized by steroid-resistant nephrotic syndrome (SRNS) are prone to progress to ESRD. Mechanism for the FSGS patients' response to steroid treatment is still unknown and currently, it is impossible to predict the steroid resistance before treatment of patients with FSGS. METHODS: To identify biomarkers and potential therapeutic targets of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32348995
DOI: 10.1159/000505956

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