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Role of Rv3351c in trafficking <i>Mycobacterium tuberculosis</i> bacilli in alveolar epithelial cells and its contribution to disease

2020-12-03

Abstract excerpt

Although interactions with alveolar macrophages have been well characterized for Mycobacterium tuberculosis , the roles epithelial cells play during infection and disease development have been less studied. We have previously shown that deletion of gene rv3351c reduces M. tuberculosis replication in and necrosis of A549 human type II pneumocyte cells. In the present study, we report that rv3351c is required fo...

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Literature Corpus work
d2899bcb-9aa3-5ba1-9c61-ce17e24d3467
DOI
10.1101/2020.12.03.409664
Open publication

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