Article

Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening

2024-09-26

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Polygenic risk scores (PRS), which provide an individual probabilistic estimate of genetic susceptibility to develop a disease, have shown effective risk stratification for glaucoma onset. However, there is limited best practice evidence for reporting PRS and patient-friendly reports for communicating effectively PRS are lacking. Here we developed patient-centred PRS reports f...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d26cea17-a683-5fe5-ba64-7737ef887fc2
DOI: 10.1101/2024.09.25.24314343

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development and evaluation of patient-centred polygenic risk score reports for glaucoma screeningDOI 10.1101/2024.09.25.24314343Read

Attitudes towards glaucoma genetic risk assessment in unaffected individualsSemantic proximity Read

Impact of polygeNic risk score for glaucoma on psycHosocial ouTcomes (INSiGHT) study protocol.Semantic proximity Read

Healthcare professionals' knowledge and attitudes towards polygenic risk testing for glaucoma.Semantic proximity Read

Design and user experience testing of a polygenic score report: a qualitative study of prospective usersSemantic proximity Read

Uptake of Polygenic Risk Testing for Glaucoma in Unaffected Individuals.Semantic proximity Read

The co-design, development, and preliminary evaluation of a comprehensive breast cancer risk report incorporating polygenic risk informationSemantic proximity Read

Short-term psychosocial outcomes following disclosure of glaucoma polygenic risk score, INSiGHT StudySemantic proximity Read

Polygenic risk scores for glaucoma: Impact on diagnosis and disease course.Semantic proximity Read

Step change in glaucoma polygenic risk score performance enables clinical utility and disease prediction across all major ancestriesSemantic proximity Read

Recall by polygenic risk score in two biobanks supports a genomic approach for glaucoma detectionSemantic proximity Read

Development and pilot testing of a prostate cancer polygenic risk reportSemantic proximity Read

Polygenic risk scores in the clinic: a systematic review of stakeholders' perspectives, attitudes, and experiences.Semantic proximity Read