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Article

Development and evaluation of patient-centred polygenic risk score reports for glaucoma screening.

BMC medical genomics - 30 Jan 2025

Hollitt Georgina L, Hassall Mark M, Siggs Owen M, Craig Jamie E, Souzeau Emmanuelle

Abstract excerpt

BACKGROUND: Polygenic risk scores (PRS), which provide an individual probabilistic estimate of genetic susceptibility to develop a disease, have shown effective risk stratification for glaucoma onset. However, there is limited best practice evidence for reporting PRS and patient-friendly reports for communicating PRS effectively are lacking. Here we developed patient-centred PRS reports for glaucoma screening...

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Topics

Humans
Glaucoma
Female
Male
Middle Aged
Multifactorial Inheritance
Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Risk Assessment

Risk Factors

Genetic Testing

Patient-Centered Care

Genetic Risk Score

Source

Open in PubMed Open full text

Identifiers

PMID: 39885483
DOI: 10.1186/s12920-024-02079-z
PMCID: PMC11783763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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