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Article

The development and evaluation of polygenic risk score reports: A systematized review of the literature.

Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jul 2025

Hanley Mia, Limb Sharne, Purvis Rebecca, Saya Sibel, James Paul Andrew, Forrest Laura Elenor

Abstract excerpt

PURPOSE: The return of polygenic risk scores (PGS) is currently being assessed in research settings for clinical utility and validity, and it is anticipated that PGS will soon be implemented in a clinical setting. There are limited guidelines regarding PGS communication and reporting; thus, there is a need to identify and analyze the current research to determine the most acceptable means of presenting PGS...

Read the complete abstract on PubMed

Topics

Humans
Multifactorial Inheritance
Genetic Testing
Risk Assessment
Genetic Predisposition to Disease
Genetic Risk Score

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40196936
DOI: 10.1016/j.gim.2025.101426

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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