Article

EML4–ALK Fusion Rewires Transcriptomic, miRNA, and CAF-Associated Programs in Non-Small Cell Lung Cancer

2026-04-16

Abstract excerpt

This study establishes an integrative framework that combines paired mRNA/miRNA profiling with immune microenvironmental features to clarify how EML4–ALK fusions shape transcriptomic and post-transcriptional networks in Non-small cell lung cancer (NSCLC). Using paired mRNA-seq and miRNA-seq data generated from the same patients, we compared fusion-positive and fusion-negative NSCLC across three interconnected laye...

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Literature Corpus work: d25740ab-32bc-53e5-bd5a-7a1e15767a8c
DOI: 10.64898/2026.04.10.717853

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