Article

<i>Ccdc38</i> is required for sperm flagellum biogenesis and male fertility in mouse

2022-01-11

Abstract excerpt

Sperm flagellum is essential for male fertility, defects in flagellum biogenesis are associated with male infertility. Deficiency of CCDC42 is associated with malformation of the mouse sperm flagella. Here, we find that the testis-specific expressed protein CCDC38 (coiled-coil domain containing 38) interacts with CCDC42 and localizes on manchette and sperm tail during spermiogenesis. Inactivation of CCDC38 in male...

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Literature Corpus work: d251ffe2-835c-5d40-a5aa-245e78cb8d93
DOI: 10.1101/2022.01.10.475757

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