Article

Recombinant FOXN1 fusion protein increases T cell generation in aged mice

2023-02-08

Abstract excerpt

<h4>Background: </h4> Although the thymus continues to export T cells throughout life, it undergoes a profound involution/atrophy with age, resulting in decreased numbers of T cells in the older adult, which has direct etiological linkages with many diseases. T cell development in the thymus is dependent on the thymic microenvironment, in which thymic epithelial cells (TECs) are the major component. However, TECs...

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Literature Corpus work: d2313a58-e549-5c59-8016-2522b0912f43
DOI: 10.21203/rs.3.rs-2557067/v1

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