Back to search

Article

Sex differences in behavioral and brainstem transcriptomic neuroadaptations following neonatal opioid exposure in outbred mice

2021-04-04

Abstract excerpt

<h4>ABSTRACT</h4> The opioid epidemic led to an increase in the number of Neonatal Opioid Withdrawal Syndrome ( NOWS ) cases in infants born to opioid-dependent mothers. Hallmark features of NOWS include weight loss, severe irritability, respiratory problems, and sleep fragmentation. Mouse models provide an opportunity to identify brain mechanisms that contribute to NOWS. Neonatal outbred Swiss Webster Cartworth...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
61889a6c-9de4-582a-96e8-109264c73754
DOI
10.1101/2021.04.02.438265
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Sex differences in behavioral and brainstem transcriptomic neuroadaptations following neonatal opioid exposure in outbred miceDOI 10.1101/2021.04.02.438265
Sex Differences in Behavioral and Brainstem Transcriptomic Neuroadaptations following Neonatal Opioid Exposure in Outbred MiceSemantic proximity
Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in miceSemantic proximity
Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW miceSemantic proximity
The ultrasonic vocalization (USV) syllable profile during neonatal opioid withdrawal and a kappa opioid receptor component to increased USV emissions in female miceSemantic proximity
In utero exposure to morphine leads to sex-specific behavioral alterations that persist into adulthood in cross-fostered miceSemantic proximity
Perinatal Fentanyl Exposure Drives Enduring Addiction Risk and Central Amygdala Gene DysregulationSemantic proximity
Neurobehavioral effects of neonatal opioid exposure in mice: Influence of the OPRM1 SNPSemantic proximity
The acoustic properties, syllable structure, and syllable sequences of ultrasonic vocalizations (USVs) during neonatal opioid withdrawal in FVB/N mouse substrainsSemantic proximity
Maternal Opioid Exposure Culminates in Perturbed Murine Neurodevelopment and Hyperactive Phenotype in Adolescence.Semantic proximity
Maternal Continuous Oral Oxycodone Self-Administration Alters Pup Affective/Social Communication but not Spatial Learning or Sensory-Motor FunctionSemantic proximity
Chronic oral fentanyl consumption produces dynamic behavioral adaptations during abstinence in female miceSemantic proximity
Early life stress induces social behavioral deficits and peripheral biomarker alterations in adolescence that perpetuate intergenerationallySemantic proximity
Select a neighboring publication to make it the new centre.